tuberculosis

Objective. To conduct a comparative evaluation of the results of phenotypic and molecular genetic methods for testing drug resistance of Mycobacterium tuberculosis isolated from bone biopsies of patients with tuberculous spondylitis. Materials and Methods. A retrospective cohort study was conducted on the case histories of patients diagnosed with tuberculous spondylitis who underwent surgical treatment in the period from 2016 to 2021. The main study subject was surgical material. Antimicrobial resistance patterns of MBT isolates was performed using phenotypic and molecular genetic methods.

Rapid tests detecting Mycobacterium tuberculosis and drug resistance which are universally implemented in medical practice has dramatically improved the diagnosis of rifampicin-resistant tuberculosis and shortened turnaround time thus enabling early …

This article describes a clinical case of fatal polymicrobial pneumonia in a patient with progressive pulmonary tuberculosis. The clinical case represents a co-infection with tuberculosis, viral and pneumocystis infection in a HIV-uninfected patient …

This article describes clinical development stages for the novel anti-TB drug «Perchlozone®», which has been approved in Russian Federation in 2012. Based on the phase I–III clinical studies results, efficacy and safety of the drug were assessed, and …

The study aimed to compare efficacy of microbiologic and molecular genetic methods in identification of an infectious agent in blood samples from HIV-positive patients with septic symptoms. 130 venous blood samples were studied using microbiological …