treatment

Probiotics as a means of strengthening commensal skin microbiota in the treatment of infected soft tissue wounds

Probiotics can promote wound healing by stimulating the production of immune cells, activation of reparative regeneration processes as well as show antagonism against pathogenic microflora. The data presented in this review of the literature indicate …

Fecal microbiota transplantation as a treatment option for patients with recurrent Clostridioides difficile-associated diarrhea

This paper provides a review of the largest studies (over the period of 2017 to 2022) on the use of fecal microbiota transplantation (FMT) for the treatment of patients with recurrent *Clostridioides difficile*associated diarrhea (CDAD), including …

С. difficile infection: clinical and pharmacoeconomic assessment of treatment regimens in antibiotic-associated diarrhea

This paper provides a review of the largest studies (over the period of 2017 to 2022) on cost-effectiveness analysis of the recommended treatment algorithms for Clostridioides difficile infection in patients with antibiotic-associated diarrhea (AAD), …

Review of the international clinical practice guidelines for the treatment of lung infections caused by nontuberculous mycobacteria

Non-tuberculous mycobacteria (NTM) include more than 190 species and subspecies. Some NTM species can cause human diseases of the lungs or extrapulmonary infections. The guidelines focus on pulmonary mycobacteriosis in adult patients without cystic …

Pharmacoepidemiology of peptic ulcer in Smolensk: 15 years later

Objective. To study management of patients with peptic ulcer based on outpatient card data and to evaluate changes in methods for diagnosis of H. pylori and treatment prescriptions compared with 2004– 2005. Materials and Methods. A total of 100 outpatient cards of patients aged 18 years and older who came to outpatient clinic visit for peptic ulcer over the period of 2015–2018 were analyzed. The results of this study were compared with the data from the pharmacoepidemiological study «Ulcer», which was performed in 2004–2005 in Smolensk.

Acute liver failure in adults

This article summarizes data on etiology, epidemiology and clinical presentation of acute liver failure. The review provides statistics on the incidence rates of acute liver failure in patients with different underlying diseases, describes the most …

Review of the Guidelines of the Spanish Society of Chemotherapy on antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa

P. aeruginosa is not only intrinsically resistant to many groups of antimicrobials, but is also extremely capable in acquiring resistance to almost all antibacterial agents that are used for the therapy of infections caused by this pathogen, making …

Current approaches to prophylaxis and treatment of travelers’ diarrhea

Travelers’ diarrhea is the most common infectious disease in this subpopulation and usually develops within the first week of travel. This review presents summarized data on epidemiology and etiology of travelers’ diarrhea. Nonspecific precautions …

Daptomycin in the treatment of infective endocarditis

This review characterizes daptomycin as a highly effective lipopeptide antibiotic being active against Gram-positive microorganisms, including multidrug resistant strains. The data reflecting the up-to-date daptomycin-based approaches to …

Problems of Management of β-herpesviral Infections

The article presents the current classification of herpesviruses, clinical features of infections caused by β-herpesviruses, as well as methods of laboratory diagnosis and treatment of these infections.