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Involvement of Pneumocystis jirovecii in infectious and other diseases in children and adults with immunosuppression of various origin

Objective. To evaluate the involvement of P. jirovecii in the infectious and other diseases in children and adults with immunosuppression of various origin. To assess the risk of infection with P. jirovecii, pneumocystosis and its spread by healthcare workers. Materials and Methods. An analysis of the results of a study of 1,446 samples of peripheral blood sera from patients, both children and adults, who were treated in hospitals of various profiles in Moscow and represented an increased risk group for pneumocystosis.

Pneumocystis and Herpesviruses in Immunocompromised Children

Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections. Materials and Methods. We examined 30 children with immunosuppression due to congenital HIV infection and 30 children receiving immunosuppressive drug therapy after liver transplantation. Results. Identified a high prevalence of markers of GWI and pneumocystosis in children with immunosuppression of various etiologies.

Empirical, Pre-emptive and Prophylactic Therapy of Invasive Mycoses: Current State of the Problem

Invasive mycoses in patients with severe diseases – ICU patients, patients with hematological malignancies and after solid organ transplantations represent a significant target for the use of prophylactic, empirical and pre-emptive antifungal …