Streptococcus pyogenes

Antimicrobial resistance of clinical Streptococcus pyogenes isolates in Russia: the results of multicenter epidemiological study «PEHASus 2014–2017»

Objective. To evaluate antimicrobial resistance patterns of clinical Streptococcus pyogenes isolates from different regions of Russia during 2014–2017. Materials and Methods. A total of 792 clinical S. pyogenes isolates from 14 Russian cities were included in the study. Susceptibility testing was performed using reference broth microdilution method (ISO 207761:2006). Susceptibility testing results were interpreted using EUCAST v.10.0 breakpoints. Results. Penicillin G was active against all tested isolates with the MIC50–90 values of 0.

Antimicrobial Susceptibility of Group A Streptococci of Different emm Genotypes, Isolated from Patients with Invasive and Non-Invasive Skin and Soft Tissue Infections

Objective. Aim. To evaluate the antimicrobial susceptibility of group A streptococci (GAS) of different emm-genotypes, isolated from patients with invasive and non-invasive skin and soft tissue infections. Materials and Methods. Overall 91 strains of GAS isolated during 2008–2011 from patients with invasive and non-invasive skin and soft tissue infections hospitalized in one Moscow’s hospital were included in the study. Identification was done by latex agglutination, genotyping — by CDC protocol.

Susceptibility of Streptococcus pyogenes Clinical Strains to Hexetidine and to Systemic Antimicrobals

Minimal inhibitory concentrations (MIC) was used to describe the activity of 8 systemic antimicrobials and antiseptic hexetidine against clinical strains of Streptococcus pyogenes. All tested agents showed high activity against Group A streptococci, …

Antimicrobial Resistance of the Respiratory Strains of Streptococcus pyogenes in Russia During 1999–2009

Objective. Objectives. To evaluate the level, structure and phenotypes of antimicrobial resistance in clinical respiratory strains of Streptococcus pyogenes in different regions of Russia during 1999–2009. Materials and Methods. In total 804 respiratory strains of S. pyogenes from different regions of Russia were included in the study. Susceptibility to 18 antimicrobials was evaluated by the standard broth microdilution method according to EUCAST 2012 recommendations. Results. β-Lactams remaine highly active against all tested strains.

Current Issues of the Diagnosis of Infections Caused by Group A Streptococci

Currently, culture remains a standard diagnostic method for streptococcal infections. However, over the last decade, rapid diagnostic tests, which are based on direct detection of a streptococcal antigen in tonsil and/or throat swabs, are more …

Streptococcus pyogenes: Characteristics of the Pathogen, Isolation, Identification and Susceptibility Testing

Streptococcus pyogenes (group A streptococcus) is one of the most important bacterial pathogen in human. In light of recent reports suggesting global changes in the epidemiology of streptococcal infections, and given the increase in severe clinical …

Comparative Efficacy of 0.75% Chloramphenicol Ointment and 2% Mupirocin Ointment in the Treatment of Community-Acquired Skin and Soft Tissue Infections

The aim of this study was to assess clinical efficacy of topical chloramphenicol in comparison to topical mupirocin in the treatment of mild to moderate communityacquired skin and soft tissue infections (SSTI). A total of 150 adult immunocompetent …

Current Approaches to Diagnosis of Streptococcal Pharyngitis

The antimicrobial agent prescription rate in patients with pharyngitis is excessively high in Russia. Most cases of the disease are caused by viruses, thus administration of antimicrobials is often unjustified. The only common bacterial cause of …

Pyoderma in Outpatients

Despite the wide use of antibiotics pyoderma remains one of the important problems of modern medicine. Patients with skin and soft tissue infections, including pyoderma, come to 13 of all patients with infectious diseases in economically …