skin and skin structure infections

New and old oxazolidinones: tedizolid vs. linezolid

Tedizolid is a novel oxazolidinone that has been recently approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by Gram-positive pathogens, including MRSA. The mechanism of action of tedizolid is similar to …

Evidence Based Review on Daptomycin Use in the Treatment of Gram(+) Infections

Daptomycin is the only clinically used member of a cyclic lipopeptides class of antibiotics. Daptomycin has rapid bactericidal activity against not only rapidly growing, but also against slow growing bacterial cells including those in biofilms. …

Ceftaroline – «Sui Generis»

Ceftaroline fosamil is a novel cephalosporin antibiotic that has a high activity against multiple bacterial pathogens, including important drug-resistant microorganisms. The main benefit of the ceftaroline fosamil compared to other beta-lactams is an …

Daptomycin – the Review of Pharmacological, Clinical and Microbiological Characteristics

Daptomycin is the first approved member of a cyclic lipopeptides class of antibiotics with anti-Gram(+) activity. In contrast to majority of other antimicrobials daptomycin has rapid bactericidal activity against not only rapidly growing, but also …