risk factors

COVID-19 risk factors for mortality in hospitalized patients: results of a retrospective study

Objective. To identify risk factors for fatal outcome and COVID-19-associated liver damage in hospitalized adult patients with coronavirus infection. Materials and Methods. In a retrospective cohort study, 389 cases of patients with coronavirus infection complicated by bilateral viral pneumonia were studied. Demographic characteristics, clinical features of the course of the disease, anamnestic data, results of laboratory and instrumental methods of examination were analyzed and correlated with mortality. At the time of admission, the following were taken into account: fever, severity of the patient’s condition according to COVID-19 classification of severity, body mass index (BMI), oxygen saturation (SpO2), percentage of lung tissue damage according to computed tomography (CT).

Hepatitis C in immunocompromised pediatric patients: an epidemiological analysis of data from a center of pediatric hematology, oncology and immunology

Objective. To analyze the incidence of HCV in patients of the «Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology» (Center), to compare with the overall population incidence of HCV, to identify risk factors and risk groups of HCV infection in the Center’s patients. Materials and Methods. A retrospective analysis of the HCV incidence of HCV patients of the Center who were admitted to the Center between 01.

COVID19 associated pulmonary aspergillosis

The novel coronavirus (COVID-19) pandemic announced by the World Health Organization in March 2020 assigned medical community to the new tasks that require immediate solutions. Recent studies have shown that invasive aspergillosis associated with …

Hospital-Acquired Pneumonia in Trauma Patients: Results of Prospective Observational Study

Objective. To study prospectively clinical course of hospital-acquired pneumonia (HAP), mortality, and risk factors for poor outcome as well as etiology and antibiotic resistance of HAP in trauma patients; to assess antimicrobial therapy in patients with head trauma and orthopedic trauma in Smolensk Clinical Hospital of Emergency Medical Care. Materials and Methods. A prospective observational study in 96 patients with head trauma or orthopedic trauma and concurrent HAP, confirmed by clinical examination, chest X-ray, and Clinical Pulmonary Infection Scale (CPIS) score of ≥5.

Risk Factors for Development of Candidemia in Neonates with Gestational Age Less Than 32 Weeks

The presend study is a retrospective case–control study included 218 infants with gestation age less than 32 weeks hospitalised in the neonatal ICU during 1999–2002. Frequency of the candidemia was 5%. Mortality in newborns with candidemia was 91%. …

First 24-hours Lethtality in Hospitalized Patients with Community-Acquired Pneumonia

Сommunity-acquired pneumonia remains one of the most common infections in population, and despite the wide array of antimicrobials, it is associated with high lethality rate. First 24-hours mortality is an integral characteristic of the quality of …