pregnancy

Emerging Concepts in Use of Macrolides in Pregnancy and Lactation

This paper reviews general issues of the use of antimicrobial agents in pregnant women. Currently available data on safety of macrolides during pregnancy and lactation are considered with the focus on several indications for their therapeutic and …

Analysis of Anti-Infective Therapy in Pregnant Women in Primorskiy Region

Results of retrospective pharmacoepidemiological study in Far East region of Russia within 2004–2008 are presented. 1119 cases of antibacterials administration during the first trimester of pregnancy from 554 medical records were analyzed. Results of …

Current Approaches to Antimicrobial Therapy of Bacterial Vaginosis

Efficacy of antimicrobial treatment regimens in pregnant or non-pregnant women with bacterial vaginosis (BV) is difficult to evaluate. It’s due to variability of the diagnosis and cure criteria currently used in clinical studies. This paper …

Bacterial Vaginosis During Pregnancy: Current State of the Problem and the Role of Antimicrobial Chemotherapy

Pregnancy is an important risk factor for the development of bacterial vaginosis. According to the data of epidemiological studies, the prevalence of this disorder in pregnant women varies from 10% to 40% in different countries. In USA estimated …

Use of Medications in Pregnant Women: Results of the Multi-Center Pharmacoepidemiology Study in Russia

The use of any medications during pregnancy is associated with a potential risk for deleterious effect on fetus and neonate. Many women take drugs during pregnancy however no studies were conducted to examine the extent of drug prescription to …

The Use of Antimicrobials in Pregnancy

The use of antimicrobials in pregnancy is associated with a potential risk for deleterious effect on fetus and neonate. Pregnancy may be associated with changes in pharmacokinetics because of reduced renal blood flow and glomerular filtration, …

Quinolones in Childhood and Pregnancy. Is There a Rationale for Their Use?

The usage of quinolones and fluoroquinolones (FQ) in children and adolescents as well as in pregnant women is considered in this paper. Based on joint toxicity of FQ observed in immature animals this class of antimicrobial agents is officially …

Antimicrobial Therapy of Urinary Tract Infections in Pregnant Women

The regimens of antimicrobial therapy of urinary tract infections in pregnant women based on data on antimicrobial susceptibility patterns of urinary pathogens in Russia are suggested.For obstetricians, gynecologists, urologists, clinical …