pneumococci

Cefodizime is a third–generation cephalosporin for parenteral use that has become available for the first time in the Russia. This paper reviews the use of this antibiotic in clinical practice based on the current data on antimicrobial resistance in …

Chronic obstructive pulmonary disease (COPD) is a serious problem for global health. Infectious agents play a main role in the development of COPD exacerbations. Bacterial colonization of the lower respiratory tract is common in patients with stable …

Objective. To evaluate antimicrobial resistance patterns of clinical Streptococcus pneumoniae isolates from different regions of Russia during 2014–2017. Materials and Methods. We included in the study 519 clinical S. pneumoniae isolates from 18 Russian cities. Susceptibility testing was performed by reference broth microdilution method (ISO 20776-1:2006). Susceptibility testing results were interpreted according to EUCAST v.9.0 breakpoints. Results. Using EUCAST non-meningeal interpretation criteria, 65.1% of isolates tested were susceptible (S) to penicillin; in addition 28.

Objective. Objectives. To reveal serotypes of Streptococcus pneumoniaе isolated from patients with pneumococcal infections and from healthy carriers in Belarus and Ukraine. Materials and Methods. There were 314 strains of S. pneumoniae in this investigation, from patients and asymptomatic carriers at the age from 0 to 90 years. After re-identification and susceptibility testing to penicillin, serogroup and serotype was identified for each strain. Using this data the coverage of 7-, 10- and 13-vallent pneumococcal conjugate vaccines was determined.

Objective. To assess antimicrobial resistance and its trends among Streptococcus pneumoniae in different regions of Russia over the 1999-2009. Materials and Methods. A total of 2419 S. pneumoniae strains from different cities of Central, NorthWestern, Southern, Volga, Ural, Siberia, Far-Eastern regions of Russia were included into the study over the period from 1999 to 2009. Susceptibility to 23 antimicrobials was determined using microdilution method according to Clinical and Laboratory Standards Institute (CLSI) guidelines.

Objective. To determine the structure of antimicrobial resistance of clinical isolates of pneumococci in different regions of Russia. Materials and Methods. A total of 210 Streptococcus pneumoniae strains isolated in 15 centres of Central (Moscow – 5 centers, Kazan, Nizniy Novgorod, Ryzan), North-Western (Smolensk, Saint-Petersburg), Southern (Krasnodar) regions, Urals (Ekaterinburg) and Siberia (Novosibirsk, Tomsk) were included in this study. Susceptibility to 19 antimicrobials – penicillin G, amoxicillin, amoxicillin/clavulanate, cefotaxime, cefepime, erythromycin, azithromycin, clarithromycin, midecamycin, midecamycin acetate, spiramycin, clindamycin, tetracycline, ciprofloxacin, levolfloxacin, chloramphenicol, co-trimoxazole, rifampicin and vancomycin – was determined by broth microdilution in accordance with NCCLS recommendations.

Translated and reprinted with permission from «Emerging Infectious Diseases» 2000; 6:552-6.

Resistance of Streptococcus pneumoniae to antimicrobial drug is increasing. To investigate the relationship between antimicrobial use and …