MRSA

Staphylococcus aureus remains one of the most important human pathogens. Special attention is paid to a new problem – emerging and spreading of methicillin$ resistant strains of S. aureus in the community (CAMRSA). The main differences between …

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from hospitalized patients from different regions of Russia. Materials and Methods. A total of 879 clinical strains of S. aureus isolated in 2000–2001 from patients hospitalized in 17medical institutions in different parts of Russia. Susceptibility to 18 antimicrobials: oxacillin, vancomycin, teicoplanin, linezolid, erythromycin, clindamycin, lincomycin, gentamicin, mupirocin, fusidic acid, ciprofloxacin, levofloxacin, moxifloxacin, quinupristin/dalfopristin, rifampicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol was determined by agar dilution method in accordance with the NCCLS recommendations.

The widespread of multy-resistant Gram-positive pathogens, especially methicillin-resistant staphylococci made us to reconsider our attitude to such an «old» drug as fusidic acid and to draw attention to its usefulness in therapy of the …