Legionella

Objective. To assess efficacy of PCR for detection of Legionella in bronchoalveolar lavage (BAL) fluid obtained from hematological patients with pneumonia and acute respiratory failure. Materials and Methods. A total of 79 BAL samples collected from the hospitalized hematological patients with pneumonia and acute respiratory failure (during the 2011–2014) were analyzed using PCR. All BAL samples have been tested for legionellosis by culture immediately after collection, and then stored at –70 °C.

Objective. To use algorithm of microbiologic and epidemiologic methods when detecting two or more cases of legionellosis in the medical institution, in accordance with the international guidelines and to assess its efficacy. Materials and Methods. A total of 76 hematological patients with pneumonia and acute respiratory failure were tested for legionellosis using bronchoalveolar lavage (BAL) fluid culture and Legionella urinary antigen test between December 2010 and January 2013. Water samples obtained from the institution’s hot water supply system were tested for Legionella by the standard microbiology method.

Objective. To determine significance of Legionella pneumonia for hematological patients in ICUs, and to evaluate prospects of the proposed algorithm for diagnosis of legionellosis. Materials and Methods. A total of 37 hematological ICU patients were assessed for legionellosis between December 2010 and February 2012. Bronchoalveolar lavage (BAL) fluid culture and Legionella urinary antigen test (rapid immunochromatographic assay) were used to diagnose legionellosis. Results. Diagnosis of legionellosis was confirmed in 4 (11%) patients, of which 3 had fatal outcome.

The objective of the study was to determine incidence and level of contamination of hot water supply systems with Legionella pneumophila in public buildings, including medical care institutions, in Moscow region. A total of 12 public buildings or …

Objective. To determine characteristics of community-acquired Legionella pneumonia depending on severity of the disease, identify adverse reactions of long-term antimicrobial regimens, and calculate equation of prognosis of Legionella pneumonia severity upon hospital admission. Materials and Methods. A total of 61 patients with Legionella pneumonia were included and divided into 3 groups depending on the disease severity: Group 1 – 15 patients with non-severe pneumonia without systemic inflammatory response syndrome (SIRS), Group 2 – 32 patients with severe pneumonia and SIRS, Group 3 – 14 patients with very severe pneumonia.

Pathogens causing “atypical pneumonias” – mycoplasmas, legionellae, clamydiae, coxiellae play significant role in human infections. In spite of considerable differences in biology, epidemiology and clinical presentations these pathogens can be …