immunosuppression

Objective. To evaluate the involvement of P. jirovecii in the infectious and other diseases in children and adults with immunosuppression of various origin. To assess the risk of infection with P. jirovecii, pneumocystosis and its spread by healthcare workers. Materials and Methods. An analysis of the results of a study of 1,446 samples of peripheral blood sera from patients, both children and adults, who were treated in hospitals of various profiles in Moscow and represented an increased risk group for pneumocystosis.

Objective. To study significance of herpesviruses in the development of infectious complications in patients after heart transplantation based on the detection of markers of herpesvirus infections. Materials and Methods. The paper presents the results of a comprehensive examination for markers (HVI) of patients who underwent orthotopic heart transplantation at the V.I. Shumakov National Medical Center of Transplantology and Artificial Organs (Moscow). A total of 86 patients were observed. To establish the etiological diagnosis of infectious complications, all the blood serum and blood cell samples were analyzed for markers of herpesvirus infections.

Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections. Materials and Methods. We examined 30 children with immunosuppression due to congenital HIV infection and 30 children receiving immunosuppressive drug therapy after liver transplantation. Results. Identified a high prevalence of markers of GWI and pneumocystosis in children with immunosuppression of various etiologies.