ICU

Use of chlorhexidine for the prophylaxis of nosocomial infections in ICU

This review summarizes published data on the use of chlorhexidine for the prevention of nosocomial infections in the intensive care units (ICU). The use of a 0.5–2.0% alcohol solution of chlorhexidine is strongly recommended for the surgical site …

Prognostic rules for invasive candidiasis risk assessment in ICU patients

nvasive candidiasis is an extremely important problem for severe patients in intensive care units. The high rates of attributive mortality are associated not only with the severity of the patient’s condition, but also with a delayed therapy due to …

Systemic Antimicrobials Consumption and Expenditures in Intensive Care Units of Hospitals in Russian Federation and Republic of Belarus: Results of Multicenter Pharmacoepidemiological Study

To assess systemic antimicrobials (AM) consumption and expenditures in intensive care units (ICU) of multiprofile hospitals in different regions of Russian Federation and Republic of Belarus in 2009–2010 retrospective collection of data from hospital …

Escherichia coli as a Nosocomial Pathogen in ICUs

Over the last years, Gram-negative bacilli are the leading cause of nosocomial infections in different part of the world. Intensive care units (ICUs) differ from other units by continuous healthcare worker-to-patient contacts, large number of …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Empiric Therapy of Invasive Candidiasis in Intensive Care Units: Current State of Problem

The high prevalence of invasive candidiasis (IC) in intensive care units (ICU) is one of the major problems of medical mycology and the modern medicine in general. More than 10% of all infections in ICU are caused by Candida spp. Infections caused by …

Empirical, Pre-emptive and Prophylactic Therapy of Invasive Mycoses: Current State of the Problem

Invasive mycoses in patients with severe diseases – ICU patients, patients with hematological malignancies and after solid organ transplantations represent a significant target for the use of prophylactic, empirical and pre-emptive antifungal …

Clinical and Pharmacoeconomic Analysis of the Treatment of Invasive Candidiasis in Intensive Care Units

Invasive candidiasis is a third or fourth cause of sepsis in intensive care units (ICUs). Clinical and pharmacoeconomic study of treatment for invasive candidiasis was first performed using mathematical modeling in Russian economic environment. ICU …

Fungal Infections Surveillance in Intensive Care Units

Invasive candidiasis is a common nosocomial infection with high attributable mortality among ICU patients. This study was performed to determine isolation rate of Candida spp. in cardiac surgical ICUs during the period of 2001–2007 and to assess …

Epidemiology of Antimicrobial Resistance of S. aureus Isolated from ICU Patients in Russia: Results of Prospective Multicenter Study

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from ICU patients in different regions of Russia. Materials and Methods. A total of 998 clinical strains of S.aureus isolated in 2004–2005 from 998 patients hospitalized in ICU of 32 medical institutions in different parts of Russia. Susceptibility to 16 antimicrobials was determined by agar dilution method in accordance with CLSI recommendations. Results. The prevalence of MRSA among tested strains was 49.