ICU

Invasive aspergillosis in patients with COVID-19 in intensive care units: results of a multicenter study

Objective. To study risk factors, clinical and radiological features and effectiveness of the treatment of invasive aspergillosis (IA) in adult patients with COVID-19 (COVID-IA) in intensive care units (ICU). Materials and Methods. A total of 60 patients with COVID-IA treated in ICU (median age 62 years, male – 58%) were included in this multicenter prospective study. The comparison group included 34 patients with COVID-IA outside the ICU (median age 62 years, male – 68%).

Microbiological monitoring of COVID-19 patients in the ICU: a prospective observational study

Objective. To study spectrum of pathogens and the time to colonization of respiratory samples in patients with severe and critical COVID-19 as well as to analyze incidence of nosocomial infections and structure of prescribed antibacterial drugs. Materials and Methods. The prospective observational study included patients aged 18 years and older with confirmed severe and critical COVID-19 from December 2021 to February 2022. During the first 48 hours and then every 2–3 days of hospitalization, a respiratory sample was collected: sputum, tracheal aspirate (if intubated), bronchoalveolar lavage (if bronchoscopy was performed) for microscopy and microbiological examination.

Use of chlorhexidine for the prophylaxis of nosocomial infections in ICU

This review summarizes published data on the use of chlorhexidine for the prevention of nosocomial infections in the intensive care units (ICU). The use of a 0.5–2.0% alcohol solution of chlorhexidine is strongly recommended for the surgical site …

Prognostic rules for invasive candidiasis risk assessment in ICU patients

nvasive candidiasis is an extremely important problem for severe patients in intensive care units. The high rates of attributive mortality are associated not only with the severity of the patient’s condition, but also with a delayed therapy due to …

Systemic Antimicrobials Consumption and Expenditures in Intensive Care Units of Hospitals in Russian Federation and Republic of Belarus: Results of Multicenter Pharmacoepidemiological Study

To assess systemic antimicrobials (AM) consumption and expenditures in intensive care units (ICU) of multiprofile hospitals in different regions of Russian Federation and Republic of Belarus in 2009–2010 retrospective collection of data from hospital …

Escherichia coli as a Nosocomial Pathogen in ICUs

Over the last years, Gram-negative bacilli are the leading cause of nosocomial infections in different part of the world. Intensive care units (ICUs) differ from other units by continuous healthcare worker-to-patient contacts, large number of …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Empiric Therapy of Invasive Candidiasis in Intensive Care Units: Current State of Problem

The high prevalence of invasive candidiasis (IC) in intensive care units (ICU) is one of the major problems of medical mycology and the modern medicine in general. More than 10% of all infections in ICU are caused by Candida spp. Infections caused by …

Empirical, Pre-emptive and Prophylactic Therapy of Invasive Mycoses: Current State of the Problem

Invasive mycoses in patients with severe diseases – ICU patients, patients with hematological malignancies and after solid organ transplantations represent a significant target for the use of prophylactic, empirical and pre-emptive antifungal …

Clinical and Pharmacoeconomic Analysis of the Treatment of Invasive Candidiasis in Intensive Care Units

Invasive candidiasis is a third or fourth cause of sepsis in intensive care units (ICUs). Clinical and pharmacoeconomic study of treatment for invasive candidiasis was first performed using mathematical modeling in Russian economic environment. ICU …