fusidic acid

Objective. To determine in vitro activity of antimicrobials against S. aureus isolated from hospitalized patients from different regions of Russia. Materials and Methods. A total of 879 clinical strains of S. aureus isolated in 2000–2001 from patients hospitalized in 17medical institutions in different parts of Russia. Susceptibility to 18 antimicrobials: oxacillin, vancomycin, teicoplanin, linezolid, erythromycin, clindamycin, lincomycin, gentamicin, mupirocin, fusidic acid, ciprofloxacin, levofloxacin, moxifloxacin, quinupristin/dalfopristin, rifampicin, trimethoprim/sulfamethoxazole, tetracycline, chloramphenicol was determined by agar dilution method in accordance with the NCCLS recommendations.

Objective. To determine in vitro activity of fusidic acid and other antimicrobials available for topical use against S. aureus isolated from hospitalised patients. Materials and Methods. A total of 879 clinical strains of S. aureus isolated in 2000-2001 from patients hospitalised in 17 medical institutions in different parts of Russia - 4 in Central region, 2 in North-West region, 3 in South region, 2 in Volga region, 3 in Ural region, 3 in Siberian region, were included in the study.

The widespread of multy-resistant Gram-positive pathogens, especially methicillin-resistant staphylococci made us to reconsider our attitude to such an «old» drug as fusidic acid and to draw attention to its usefulness in therapy of the …