ESBL

Molecular characterization of extended-spectrum beta-lactamase-producing Enterobacterales isolates collected from blood culture in patients with hematological malignancies

Objective. The objective of the study was to evaluate the prevalance of genes blaTEM, blaSHV and blaCTX-M among extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales isolates collected from blood culture in patients with hematological malignancies. Materials and methods. The prospective multicenter study included Enterobacterales isolates collected from blood culture in hematological patients from 10 Russian hospitals (2003-2015). The isolates were screened for ESBLs by the phenotypic methods (CLSI 2017). Genes encoding TEM, SHV and CTX-M were detected using polymerase chain reaction (PCR) by specific primers.

Clinical significance and changes in antimicrobial resistance in ESBL producers isolated over the 2014-2016 in a regional teaching hospital

The role of Escherichia coli and Klebsiella pneumoniae in the etiology of respiratory tract, bloodstream, urinary tract and soft tissue infections in the Tyumen Regional Clinical Hospital has been evaluated for three years time period (2014-2016). …

Multidrug-Resistant Enterobacteriaceae Colonizing Gastrointestinal Tract in Infants with Congenital Heart Disease on Admission to Cardiac Surgery Hospital

We studied 126 children, admitted to cardiac surgery hospital with colonization of the gastrointestinal tract (GIT) by multidrug-resistant Enterobacteriaceae. Criterion for inclusion in the study were children with complex congenital heart disease …

Escherichia coli as a Nosocomial Pathogen in ICUs

Over the last years, Gram-negative bacilli are the leading cause of nosocomial infections in different part of the world. Intensive care units (ICUs) differ from other units by continuous healthcare worker-to-patient contacts, large number of …

Detection of Extended Spectrum β-lactamases by Phenotypic Methods in Gram-negative Bacteria

Production of extended-spectrum β-lactamases (ESBL) is the one of most widespread and clinically significant mechanism of resistance to modern β-lactams in members of the family Enterobacteriaceae. But the effectiveness of routine methods of …