corticosteroids

Mucormycosis is a serious fungal infection, which increased significantly during the COVID-19 pandemic. We retrospectively analyzed 5 histopathologically confirmed cases of rhino-cerebral mucormycosis, which were diagnosed in patients admitted to …

Objective. To assess efficacy and safety of methylprednisolone pulse therapy in patients with COVID-19. Materials and Methods. A retrospective analysis of 57 patients with moderate and severe novel coronavirus infection (COVID-19) receiving methylprednisolone pulse therapy (500 mg/day IV for 2–3 consecutive days) was performed. Pre- and post-therapy examination of the patients included clinical (severity and duration of fever, gas exchange parameters), imaging (computed tomography) and laboratory tests (including C-reactive protein, procalcitonin, D-dimer).

Community-acquired bacterial meningitis is one of the most serious infectious lesions of the central nervous system that can quickly lead to death in even previously healthy patients with inadequate treatment. The article provides an overview of the …

This literature review presents approaches to the treatment of sarcoidosis, which are based on currently offered hypothesis of its pathogensis.These include: influence on granulomatous inflammation (corticosteroids, cytotoxic agents, anti-malaria …

Evidence-based analysis of clinical trials, concerning appropriateness of corticosteroids use and its efficacy in the treatment of septic shock, was performed. Results of pharmacoepidemiological study of corticosteroids use in Russian hospitals are …