COPD

Antimicrobial therapy of chronic obstructive pulmonary disease exacerbations in a multidisciplinary hospital

Objective. To study the real practice of management of patients with COPD exacerbations on the example of a single hospital. Materials and Methods. During the retrospective descriptive study the data of medical records of 219 patients with COPD were processed, the profile of the studied patients with distribution by phenotypes and determination of the Charlson comorbidity index was compiled and analyzed. StatPlus 7.0 program was used for statistical analysis.

Antibiotics and community-acquired lower respiratory tract infections. To whom? Which one?

This paper discusses an etiology, patient characteristics, and antimicrobial resistance surveillance data, as well as other factors which help to determine indications for administration and choice of antibiotics for the treatment of patients with …

Analysis of Antibiotic Resistance Genes in Intestinal Microbiota in Patients with Chronic Obstructive Pulmonary Disease

This paper presents the study results of the representation relative level and drug resistance genes composition of intestinal microbiota in COPD patients with subsequent evaluation of the antibiotic therapy courses frequency effect on the risk of …

Antibacterial Therapy of Infectious Exacerbations of Chronic Bronchitis: from Pathogen Eradication to Long-Term Relapse-Free Period

Chronic obstructive pulmonary disease (COPD) is a chronic illness that is characterized by recurring exacerbations. Exacerbations lead to the progression of the disease with development of respiratory failure, decreasing of the quality of life of the …

Cephalosporins in the Treatment of Community-Acquired Upper and Lower Respiratory Tract Infections Based on Antimicrobial Resistance Data from Russia

Beta-lactams remain one of the most commonly used antimicrobial classes in the treatment of community-acquired respiratory tract infections worldwide. Among them, cephalosporins take one of the main places because of their broad spectrum of activity …

Bacterial Infection in COPD-Patients with Acute Respiratory Failure

To study the microbial and susceptibility patterns in COPD patients with acute respiratory failure (ARF) we performed a prospective cohort study in patients with ARF admitted to our acute care hospital. Quantitative cultures of expectorated sputum or …