antimicrobial resistance | CMAC

antimicrobial resistance

Antimicrobial resistance and clonal evolution of Streptococcus pneumoniae serotype 19A in Russia during 2002-2013

After the introduction of the conjugated 7-valent pneumococcal vaccine (PCV7) the incidence of infections, caused by non-vaccine serotypes of S. pneumoniae, especially by 19А serotype, significantly increased. But in few countries similar phenomenon …

Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities. …

Antimicrobial resistance of nosocomial Enterobacteriaceae isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of …

Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter …

Antimicrobial resistance of nosocomial Pseudomonas aeruginosa isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 743 isolates of P. aeruginosa collected in 63 hospitals of 22 cities of Russia …

Surveillance of antimicrobials use in neonatal hospitals with alternative DDD methods

One of the most common problems in neonatal hospitals is the choice of metrics of drugs usage in neonatology, especially use of antibiotics. This study represents our experience in quantifying antibiotic use in a Level-III neonatal intensive care …

The role of type III secretion system in the development of nosocomial infections, caused by multiresistant Pseudomonas aeruginosa strains

Type III Secretion System (TTSS) is a key pathogenicity factor of Pseudomonas aeruginosa. The suppression of the activity of TTSS would potentially allow block the infection independently on the presence of antimicrobial resistance. To study the role …

Antimicrobial Susceptibility of Helicobacter pylori Isolates from Patients with Gastric Cancer and Precancer

colonization of gastric mucosa with Helicobacter pylori in patients with precancerous conditions (adenomatous polyp, hyperplastic polyp, focal hypertrophy, erosions) and gastric cancer (adenocarcinoma, signet ring cell carcinoma, carcinoid). The …

Current Trends in Antimicrobial Resistance of Neisseria gonorrhoeae in Russian Federation

Objective. of current Neisseria gonorrhoeae isolates and determine its trends over the RU-GASP (Russian Gonococcal Antimicrobial Susceptibility Programme) period. Materials and Methods. A total of 293 strains of N. gonorrhoeae isolated in 11 regions within Central, North-Western, Volga, Southern, and Siberian federal districts over the 2015–2016 were included in this study. Susceptibility to benzylpenicillin, ceftriaxone, tetracycline, spectinomycin, azithromycin, and ciprofloxacin was determined by agar dilution method and assessed according to the CLSI, EUCAST and MUK 4.

Prognostic Model of Microbial Resistance Based on the Relationship between Antibiotic Resistance and Consumption

Acquired bacterial resistance is one of the leading causes of morbidity and mortality attributed to infectious diseases. Simulations may provide opportunity to predict further spread of resistance and, to some extent, manage it. The objective of this …