antibiotic resistance

Objective. assessment of the evolution of the microbiological landscape of the hospital for the period of operation in 2020 into a pandemic of a new coronavirus infection in various departments, including intensive care units; change depending on the results of antibacterial therapy regimens. Materials and Methods. In a retrospective study, conducted from June to December 2020, in a multidisciplinary hospital working with COVID-19 infection, the resistance of isolated strains of microorganisms was analyzed in patients of different age groups.

Objective. To review the basic principles and functionality of the AMRmap online resource. Materials and Methods. The AMRmap platform was developed using the R programming language and various downloadable modules – packages. The current annually updated version of EUCAST clinical breakpoints was applied for determination of categories of susceptibility to antimicrobial agents. Descriptive analysis includes calculation of absolute and relative frequencies, median values, and confidence intervals using the Wilson method.

Antimicrobial resistance is a growing threat to global public health and requires closer attention from the medical community. Antibiotic resistance monitoring systems play a key role in observing the antimicrobial susceptibility changes for rational …

Objective. To characterize the population structure and determine the genetic mechanisms of carbapenem resistance in nosocomial isolates of P. aeruginosa collected in Moscow in 2012-2016. Materials and methods. Carbapenem-resistant isolates were collected in two pediatric hospitals in Moscow. Antibiotics susceptibility of P. aeruginosa isolates was assessed using the E-tests and disk-diffusion method. Multilocus sequence typing (MLST) was used for genotyping of the isolates. The presence of metallo-betalactamase (MBL) genes was determined using real-time PCR.

An analysis of current trends in the prevalence of nosocomial infections, their etiology and antibiotic resistance in pathogens was performed. Social and economic consequences of antimicrobial resistance as well as a medical community’s response were …

This study analyzed a prevalence of carbapenem-resistant Klebsiella pneumoniae strains obtained in the Privolzhsky Federal Medical Research Center units and their antibiotic resistance mechanisms. During the study year, the incidence of K. pneumoniae …

This review describes the new Internet resource AMRmap (map.antibiotic.ru), which provides data on antibiotic resistance in the Russian Federation.

The activity of 11 antibiotics combinations and 4 commercially available preparations for phagotherapy in regard to metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa clinical isolates of sequence type 235 (ST 235) belonging to the clonal …

Objective. Objectives. To investigate etiology and in vitro susceptibility of the most common pathogens causing community-acquired urinary tract infections (UTIs) in Russia. Materials and Methods. A total of 182 uropathogens isolated from urine samples of patients with communityacquired UTI were collected in Russia during 2013–2014 and included in the study. Results. Among the identified microorganisms the most prevalent uropathogens were Enterobacteriaceae (87,9%) and E. coli (68,1%). Drugs active against more than 90% of all Enterobacteriaceae isolates were fosfomycin (98,1%) and ceftibuten (93,1%).

Due to increased use of antibiotics in current clinical practice it is very important to evaluate all risks of antimicrobial therapy. Pharmacovigilance plays a vital role in ensuring that doctors, together with the patient, have enough information …