Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(2):177-187
This article presents results of the study on serotypes distribution of clinical and colonized strains of S. pneumoniae circulated in different regions of Russian Federation in children attended day-care centers and orphanages, and in pediatric patients under 5 years old acute otitis media (AOM), pneumonia or invasive diseases (sepsis, meningitis, ext). During the investigation, we determined that serotypes 1, 3, 4, 5, 6 7, 9, 14, 18, 19 and 23 circulated in different regions of Russian Federation, which constituent in 7-, 10- and 13-valent polysaccharide conjugated vaccines. Vaccine coverage is 405⁄69,5%, 438⁄75,2% and 470⁄80,7% (CI = 6.3), respectively. The majority of penicillin-resistant strains of S. pneumoniae pneumococcal serotypes corresponded to vaccinal ones.