Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(1):4-13
Legionella spp. is an uncommon but important causative pathogen of respiratory tract infections occurring both sporadically and in epidemics. An interest in it has emerged recently after outbreak of legionellosis in Sverdlovsk region. In this guidelines biological characteristics of Legionella spp., description of two clinical entities of legionellosis (Pontiac fever and Legionnaires disease) and current approaches to antibacterial therapy are reviewed. Diagnostic methods and criteria of Legionnaires disease diagnosis are also discussed with an emphasis on available immunochromatographic test for the detection of Legionella pneumophila serogroup 1 in urine.