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diagnosis

Experience with the use of an automated system for diagnosis of urinar y tract infections

Objective. To compare results of microbiological examination obtained on rapid automated system with semiquantitative plate culture to assess possibility and necessity of using the system in urine examination. Materials and Methods. The study included 231 urine samples collected from February to July 2023 from patients at Lomonosov Moscow State University Medical Research and Educational Center. The samples were cultured according to the standards of urine microbiological examination using chromogenic media and using an automatic HB&L system (Alifax, Italy) for 4 h.

Disseminated Mycobacterium genavense infection in an otherwise healthy child: a clinical case and literature review

This paper presents the first clinical case of combined pulmonary and abdominal M. genavense infection in an otherwise healthy, immunocompetent child with an early treatment response and full recovery. The favorable outcome was determined by rapid …

Antimicrobial therapy of chronic obstructive pulmonary disease exacerbations in a multidisciplinary hospital

Objective. To study the real practice of management of patients with COPD exacerbations on the example of a single hospital. Materials and Methods. During the retrospective descriptive study the data of medical records of 219 patients with COPD were processed, the profile of the studied patients with distribution by phenotypes and determination of the Charlson comorbidity index was compiled and analyzed. StatPlus 7.0 program was used for statistical analysis.

Rapid syndromic approach to diagnosis of bacteremia – results of the first experience

Objective. To describe results of the first experience of using a syndromic approach to the diagnosis of bacteremia using multiplex panels for real-time polymerase chain reaction (real-time PCR). Materials and Methods. The prospective study included 10 consecutive positive blood cultures obtained from 10 patients in the intensive care unit after cardiac surgery. Hemocultures were carried out in BacT/ ALERT FA Plus vials using a BacT/ALERT 3D 120 incubator (bioMérieux, France).

Current approaches and prospects for the development of laboratory diagnosis of measles

Measles virus causes an acute infectious disease with high contagiousness. It is possible to limit the spread of measles virus only with a sufficiently wide coverage of the population by vaccination. Despite the success of measles elimination …

Enigmatic Achromobacter

This review aims to describe the microbiological characteristics, resistant features and pathogenic potential of Achromobacter spp. Achromobacter as an opportunistic pathogen can cause severe and even fatal infections. The current knowledge about …

Mucormycosis: modern diagnostics and treatment, existing problems and new trends in antifungal therapy

Over the last decade, the introduction of new antifungal drugs and diagnostic procedures has improved the prognosis of hematological patients with invasive fungal disease (IFD), primarily invasive aspergillosis. Despite effective antifungal …

Real-Time PCR for the Diagnosis of Tick-Born Infections

Overall 842 cases of admission due to tick bites in Irkutsk area during 2014 were analyzed. Detection of DNA/RNA of the tick-born encephalitis virus, Lyme borreliosis, monocytic ehrlichiosisand granulocyticanaplasmosis in the human serum and in the …

Septic Arthritis in Adults

Septic arthritis is a rheumatologic emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality. The risk of septic arthritis significantly increased in patients with premorbid affected joints (especially with …

Problems of Management of β-herpesviral Infections

The article presents the current classification of herpesviruses, clinical features of infections caused by β-herpesviruses, as well as methods of laboratory diagnosis and treatment of these infections.