Pharmacoepidemiology and Pharmacoeconomics

Objective. To estimate proportion of hard and surrogate endpoints used as effectiveness criteria in pharmacoeconomic studies of antimicrobial drugs. Materials and Methods. The pharmacoeconomic studies of 30 antimicrobial agents proposed for inclusion in the Russian essential drug list in the 2014-2016 were reviewed. Results. A total of 47 effectiveness criteria were analyzed, of them 40.4% were hard endpoints. Two studies of antifungal drugs used the hard endpoints only. The hard endpoints were used in 58.

Self-treatment with antibiotics and their OTC-dispensing is one of the major problems associated with the inappropriate use of antibiotics. The study was aimed to identify the features of the behavior of patients and pharmacists in antibiotics’ …

Analysis of antibiotic usage in children living in orphanages was performed during two time-periods: 2003–2004 and 2009–2010 with the aim to reveal key problems of antibiotic usage in this population, and to develop measures for improvement. It was …