Diseases and Pathogens

In this paper the main results of intervention campaign carried out among physicians and patients in different outpatient settings of Smolensk region are presented and discussed. The campaign aimed to improve the practice of antibacterial therapy in …

The risk of the development of diabetic foot syndrome in diabetic patients is more than 25% during the life. Almost half of all cases of diabetic foot syndrome are associated with infections with about 65% of infections involving the bone tissues. At …

Objective. Objectives. To determine the diagnostic and treatment patterns for acute male urethritis (AMU) in Russia. Materials and Methods. Retrospective cross-sectional study was conducted during 2009 in 4 cities of Russia: Kaluga, Pskov, Smolensk and Tula. Data on diagnostic and treatment approaches for AMU subjects ≥16 years old were collected and analyzed using specially designed case report forms. Results. 556 cases of AMU were analyzed during study period. The average age of patients was 29 years (16–68 years).

The high prevalence of invasive candidiasis (IC) in intensive care units (ICU) is one of the major problems of medical mycology and the modern medicine in general. More than 10% of all infections in ICU are caused by Candida spp. Infections caused by …

Prophylaxis of nosocomial legionellosis is a currently adopted component of the general strategy to fight hospital-acquired infections. In the early 1980s, nosocomial outbreaks of legionnaire disease associated with the high mortality (20 to 40%) …

Objective. Objectives: We aimed to reveal the current practice of diagnosis and management of bacterial sexually transmitted diseases (STDs) in different regions of Russia and to compare it with the current national guidelines. Materials and Methods. A multicenter retrospective study was conducted in 10 different cities of Russia. Randomly selected clinical records of 1250 adult patients (61% male, 39% female, mean age 28.8±9.2) treated for early syphilis (n=341), uncomplicated gonococcal (n=309), chlamydial (n=310), mycoplasma (n=137) and ureaplasma (n=153) infection during the period since January 2007 till December 2007 were analyzed.

Objective. To determine characteristics of community-acquired Legionella pneumonia depending on severity of the disease, identify adverse reactions of long-term antimicrobial regimens, and calculate equation of prognosis of Legionella pneumonia severity upon hospital admission. Materials and Methods. A total of 61 patients with Legionella pneumonia were included and divided into 3 groups depending on the disease severity: Group 1 – 15 patients with non-severe pneumonia without systemic inflammatory response syndrome (SIRS), Group 2 – 32 patients with severe pneumonia and SIRS, Group 3 – 14 patients with very severe pneumonia.

Objective. To study prospectively clinical course of hospital-acquired pneumonia (HAP), mortality, and risk factors for poor outcome as well as etiology and antibiotic resistance of HAP in trauma patients; to assess antimicrobial therapy in patients with head trauma and orthopedic trauma in Smolensk Clinical Hospital of Emergency Medical Care. Materials and Methods. A prospective observational study in 96 patients with head trauma or orthopedic trauma and concurrent HAP, confirmed by clinical examination, chest X-ray, and Clinical Pulmonary Infection Scale (CPIS) score of ≥5.

In vitro activity of 13 antimicrobials (amikacin, cefepime, cefoperazone, cefoperazone/sulbactam, cefotaxime, ceftazidime, ciprofloxacin, gentamicin, imipenem, levofloxacin, meropenem, piperacillin, piperacillin/tazobactam) against 464 Acinetobacter …

Central venous access is commonly used in clinical practice for a wide spectrum of procedures, such as hemodialysis, long-term chemotherapy, parenteral nutrition, etc. The main complications limiting the duration of use of central catheters and …