Diseases and Pathogens | CMAC

Diseases and Pathogens

Paediatricians Approach to Prescribing of Systemic Antimicrobials in Outpatient Children with Upper Respiratory Tract and ENT Infections: Data from Multicenter Survey

Objective. Objectives. The study aimed to assess paediatricians knowledge of etiology and approach to systemic antimicrobials (АМ) use in outpatient children with acute respiratory tract infections. Materials and Methods. A questionnaire survey of primary care paediatricians from 17 cities of Russian Federation was performed in 2011–2013 in compliance with the unified methodology. Results. A total of 701 paediatricians (mean age 46,3±10,7, 61,5% with work experience >15 years) took part in the survey.

Matrix of Microbial Biofilms

This literature review was aimed to summarize information on an extracellular matrix, which is one of the most important components of microbial biofilms. Structural and biochemical characteristics of biofilms matrix produced by the most common …

Resolution of the Public Coordinating Board on Pneumococcal Infection and Vaccination in Russia

Pneumocystis and Herpesviruses in Immunocompromised Children

Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections. Materials and Methods. We examined 30 children with immunosuppression due to congenital HIV infection and 30 children receiving immunosuppressive drug therapy after liver transplantation. Results. Identified a high prevalence of markers of GWI and pneumocystosis in children with immunosuppression of various etiologies.

Septic Arthritis in Adults

Septic arthritis is a rheumatologic emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality. The risk of septic arthritis significantly increased in patients with premorbid affected joints (especially with …

Pseudomonas aeruginosa: Pathogenicity, Pathogenesis and Diseases

Pseudomonas aeruginosa is one of the most important pathogens causing opportunistic infections. This literature review contains analysis of articles on molecular characteristics of P. aeruginosa virulence factors, as well as the pathogenesis of …

Problems of Management of β-herpesviral Infections

The article presents the current classification of herpesviruses, clinical features of infections caused by β-herpesviruses, as well as methods of laboratory diagnosis and treatment of these infections.

Etiology of Infective Endocarditis in Russia

Objective. To investigate etiology of infective endocarditis in Russian Federation. Materials and Methods. Multicenter prospective (September 2011 to December 2013) and retrospective (January 2006 – September 2011) studies to investigate etiology of infective endocarditis (IE) were performed at medical institutions in 10 Russian cities. Patients with definite or possible diagnosis of IE who have at least 1 blood culture collected were enrolled in the study. Results. A total of 401 patients with IE were included in the analysis: 161 (40.

Bacteriological and Molecular Diagnosis of Bacteremia in HIV-positive Patients

The study aimed to compare efficacy of microbiologic and molecular genetic methods in identification of an infectious agent in blood samples from HIV-positive patients with septic symptoms. 130 venous blood samples were studied using microbiological …

Viral Hepatitis E in Patients with Secondary Immunodeficiency

This paper presents a comparative analysis of distribution of hepatitis A, B, C and E as well as opportunistic infections among immunosuppressed patients and healthy people. Results of this epidemiological study suggest hepatitis E as an …