Diseases and Pathogens | CMAC

Diseases and Pathogens

Bacteriological and Molecular Diagnosis of Bacteremia in HIV-positive Patients

The study aimed to compare efficacy of microbiologic and molecular genetic methods in identification of an infectious agent in blood samples from HIV-positive patients with septic symptoms. 130 venous blood samples were studied using microbiological …

Viral Hepatitis E in Patients with Secondary Immunodeficiency

This paper presents a comparative analysis of distribution of hepatitis A, B, C and E as well as opportunistic infections among immunosuppressed patients and healthy people. Results of this epidemiological study suggest hepatitis E as an …

Administration of Antimicrobials into Respiratory Tract: Methods to Improve Efficacy in the Treatment of Hospital-Acquired Pneumonia

Despite the availability of substantial theoretical benefits, the method of antibacterial administration via the respiratory tract to treat acute pneumonia has yet to be widely implemented in clinical practice. The introduction of the method is …

Current Approaches to Diagnosis and Treatment of Respiratory Tract Infections in Patients with Cystic Fibrosis

Chronic airway inflammation and infection are the main cause of mortality in patients with cystic fibrosis (CF), therefore effective antimicrobial therapy is important part of treatment of CF-lung disease. In the article, an overview on present …

Level of Knowledge of Medical Specialists on the Etiology, Diagnosis and Treatment of Infectious Endocarditis in Russia

Objective. To reveal the level of knowledge of medical specialists on the diagnostics and treatment of infective endocarditis (IE). Materials and Methods. Multicenter interviewing of the medical specialists about IE etiology, diagnostics and treatment was conducted during 2012–2013 in 15 cities of different regions of Russia. Results. Overall 530 medical specialists were interviewed. On the question concerning the choice of echocardiographic study only 59,4% of respondents have marked transesophageal route.

Choice of Antimicrobial Agents in Uncomplicated Urinary Tract Infections: How to Make Decision Worthy of Solomon?

Antimicrobials for the treatment of uncomplicated urinary tract infections (UTI) include different drug classes: fluoroquinolones, cephalosporins, beta-lactam/betalactamase inhibitor combinations, aminoglycosides, carbapenems, nitrofurans, …

Distribution of Immune Evasion Cluster Genes and Genes Encoding Other Virulence Factors among Staphylococcus aureus

Siphoviridae family bacteriophages are known to play a major role in horizontal transfer of virulence genes among Staphylococcus aureus. Integrase group 3 phages transfer genes encoding staphylokinase (sak), staphylococcal complement inhibitor (scn), …

Lymphogranuloma Venereum: Epidemic of the Old Disease in New Regions

This paper reviews a current state of the lymphogranuloma venereum in developed countries. Lymphogranuloma venereum is a sexually transmitted disease caused by Chlamydia trachomatis serovars L1, L2, and L3. Over the last years, this infection has …

Incidence of Community-Acquired Pneumonia and Acute Otitis Media in Children 0–5 Years in Russia and Role of S. pneumoniae or H. influenzae in the Etiology of the Diseases

Objective. To estimate the incidence of communityacquired pneumonias and acute otitis media and the role of S. pneumoniae and H. influenzae in these infections in children under 5 years. Materials and Methods. Investigational program PAPIRUS (Prospective Assessment of Pneumococcal Infection in RUSsia), which included multi-center prospective epidemiological study estimating the incidence of community-acquired pneumonia (CAP) and the role of S. pneumoniae and H. influenzae in CAP and acute otitis media (AOM) in children 0-5 years of age in 3 Russian cities (Barnaul, Yekaterinburg and Murmansk) and the prospective multi-center observational cohort study evaluating the incidence of AOM in children under 5 years in the same cities had been performed during 12 months.

Treatment of Acute Tonsillitis/Pharyngitis: Current Guidelines and Russian Local Situation

The article analyzes contemporary recommendations for diagnosis and treatment of acute tonsillopharyngitis, and essential practical aspects for management of patients with this infection considering characteristics of antibiotic resistance profile of …