immunosuppression | CMAC

immunosuppression

Significance of herpesvirus infections in the etiology of bronchopulmonary complications in patients undergoing heart transplantation

Objective. To study significance of herpesviruses in the development of infectious complications in patients after heart transplantation based on the detection of markers of herpesvirus infections. Materials and Methods. The paper presents the results of a comprehensive examination for markers (HVI) of patients who underwent orthotopic heart transplantation at the V.I. Shumakov National Medical Center of Transplantology and Artificial Organs (Moscow). A total of 86 patients were observed. To establish the etiological diagnosis of infectious complications, all the blood serum and blood cell samples were analyzed for markers of herpesvirus infections.

Pneumocystis and Herpesviruses in Immunocompromised Children

Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections. Materials and Methods. We examined 30 children with immunosuppression due to congenital HIV infection and 30 children receiving immunosuppressive drug therapy after liver transplantation. Results. Identified a high prevalence of markers of GWI and pneumocystosis in children with immunosuppression of various etiologies.