The effect of the tinctorial properties of microorganism on the nutritional status and the early outcome in patients with SIRS of bacterial origin | CMAC

The effect of the tinctorial properties of microorganism on the nutritional status and the early outcome in patients with SIRS of bacterial origin

Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(4):359-365

​ Ketsko Yu.L., Zhestkov A.V., Gusyakova O.A., Lunina A.V., Lyamin A.V.
10.36488/cmac.2019.4.359-365
microorganism tinctorial properties SIRS protein-energy undernutrition nutritional status macronutrients
Section
Personal Experience
Type
Original Article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(4):359-365

Objective.

To determine the effect of the tinctorial properties of microorganism on the nutritional status and the early outcome in patients with systemic inflammatory response syndrome (SIRS) of bacterial origin.

Materials and Methods.

A retrospective statistical analysis of case histories of 137 patients with signs and symptoms of SIRS and bacterial infections (caused by a single pathogen) was performed. The following clinical and laboratory parameters of protein-energy undernutrition (PEU) were determined and assessed: body mass index, body weight deficit, total protein, serum albumin, absolute peripheral blood lymphocyte count. Basic metabolic rate indicators (daily energy demand, macronutrient demand) were calculated by indirect calorimetry. The severity of patients at hospital admission is assessed using the SOFA.

Results.

The statistically significant effect of the tinctorial properties of microorganism on the nutritional status and the early outcome in patients with SIRS of bacterial origin was confirmed.

Conclusions.

The type of microorganism determined by tinctorial properties has a different effect on patient’s metabolic status. Patients with Gram-negative infections have an increased protein and protein caloric intake. Patients with Gram-positive infections have an increased energy requirements and macronutrient intake. The indicators of the baseline PEU in patients with SIRS of bacterial origin have a significant effect on the disease outcome. The study results stress the importance of nutritional therapy directed to adjustment of daily caloric intake and the percentage of protein calories in patients with systemic bacterial inflammation.

Yurij L. Ketsko

Samara State Medical University, Samara, Russia

Zhestkov A.V.

Samara State Medical University, Samara, Russia

Gusyakova O.A.

Samara State Medical University, Samara, Russia

Lunina A.V.

Samara State Medical University, Samara, Russia

Artem V. Lyamin

Samara State Medical University, Samara, Russia

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