Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(4):485-493
Objective. To investigate antibiotic resistance of S. aureus isolates from cystic fibrosis (CF) patients with chronic lung infection and to identify its genetic determinants.
Materials and Methods. The antibiotic susceptibility of 629 S. aureus isolates from pediatric and adult CF patients was analyzed using the disk diffusion method and E-test in accordance with EUCAST guidelines. All strains were screened by PCR for the presence of the mecA and mecC genes.