severe infections

Microbiological and Clinical Issues on the Use of Piperacillin/Tazobactam in the Treatment of Severe Infections

Piperacillin/tazobactam, penicillin/beta-lactamase inhibitor combination, has a broad antimicrobial spectrum, including most gram-positive cocci and gram-negativeaerobic and anaerobic bacteria (including beta-lactamase producing microorganisms). …

Meropenem in the Treatment of Severe Infections in Children

Carbapenems are the most appropriate antimicrobials for empiric and pathogen-directed monotherapy in most severe and life-threatening infections in pediatric patients. It can be explained by broadest spectrum of activity, including multidrug …

Infectious Complications of the Anti-TNF Therapy: «Praemonitus, Praemunitus»

Tumor necrosis factor (TNF)-blocking agents are one of the new option in the treatment of immune-mediated inflammatory diseases, such as rheumatoid arthritis, Crohn disease, ulcerative colitis. However, anti-TNF therapy is associated with the …