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S aureus

Macrocidins A and Z: assessment of antibacterial and antibiofilm activity

Objective. To compare antibacterial activity of macrocidins A and Z against staphylococci and their effect on staphylococcal biofilms. Materials and Methods. The antibacterial activity of macrocidins A and Z produced by Didymella baileyae VIZR 1.53 was studied by serial dilution method against 120 staphylococcal cultures isolated from orthopedic patients. The effect of macrocidins on biofilm formation of 60 S. aureus clinical cultures was assessed by O’Toole method by co-incubation of active substances with bacteria and subsequent MBIC50/90.

Antimicrobial resistance of staphylococci in pediatric hospitals

Objective. To determine frequency of Staphylococcus isolation and antimicrobial resistance in hospitalized children with different types of infections. Materials and Methods. Species identification and antimicrobial susceptibility testing in staphylococci were performed on a WalkAway 96 analyzer using Pos Combo type 20 tablets, and mecA gene detection was performed on a RotorGene 6000 amplifier with a set of AmpliSens MRSA-screen FL. Results. A total of 876 strains of staphylococci isolated in children’s hospitals were tested.

Susceptibility to antiseptic preparations in biofilm-forming Staphylococcus aureus and Pseudomonas aeruginosa isolated from burn wounds

The article presents data on susceptibility to antiseptic preparations in antibiotic-resistant S. aureus and P. aeruginosa strains isolated from burn wounds, which were tested in single-species and double-species biofilms with varying degrees …