review

Spiramycin, natural 16-membered macrolide antibiotic, was discovered in 1954. This antimicrobial agent is at least non-inferior to and has some advantages over the currently available macrolides in spectrum of activity, pharmacological properties, …

Aspiration is defined as accidental entry of oropharyngeal secretions or gastric juice (endogenous substances) or water, food (exogenous substances) into the lower respiratory tract. The clinical response to aspiration is dependent on the interplay …

In spite of development of number of new antimicrobials of other classes, aminoglycosides are still widely used in clinical practice. Their rapid bactericidal activity against the majority of common human pathogens as well as synergism with some …

Macrolides are widely used antibiotics in a variety of infections, especially community-aquired. The clinical success of macrolides is due to their activity against classical causative agents, intracellular pathogens, and some protozoa. Of great …

Azithromycin is one of the most commonly used macrolides in the treatment of respiratory tract infections. Azithromycin is a popular antimicrobial due to a number of its unique pharmacokinetic and pharmacodynamic properties. This review describes the …

Carpabenems (imipenem, meropenem, ertapenem) are currently one of the antibiotic classes that exhibit the broadest spectrum of activity and characterized by the low resistance rates of clinically significant pathogens. This article is an attempt to …

Spiramycin is classic representative of the 16-membered macrolides, which was synthesized in 1954. Nevertheless he keeps his clinical significance due to the high activity against typical causative agents of respiratory tract, skin and soft tissues …

According to the guidelines of ESCAR (ESCMID Study Group on Coxiella, Anaplasma, Rickettsia and Bartonella and the European Network for Surveillance of Tick-Borne Diseases)

Ticks are obligate haematophagous acarines that parasitise every class of …