Development of Chlamydial Arthritis Model in Rats

Objective. To develop and characterize experimental model of chlamydial arthritis in rats. Materials and Methods. Wistar male rats received an intra-articular injection of 0.15–0.20 ml of purified elementary bodies of Chlamydophila (Chlamydia) trachomatis L2/Bu-434 or Chlamydophila (Chlamydia) muridarum Nigg. Animals were divided into two groups: young rats (body weight: 350-380 g) and adult rats (body weight: 450–500 g). Results. No changes in the affected joints were observed in rats infected with C.