quinolones

Independent Acquisition of Quinolone Resistance in Clonally Related Nosocomial Strains of Salmonella Typhimurium Due to Hypermutability

Here we report on a high incidence of quinolone resistance (43,1%) among nosocomial CTX-M-5 ESBLproducing S. Typhimurium isolates belonging to a single clonal group isolated in Russia, Belarus, and Kazakhstan. The resistance mechanism in all cases …

Quinolones in Childhood and Pregnancy. Is There a Rationale for Their Use?

The usage of quinolones and fluoroquinolones (FQ) in children and adolescents as well as in pregnant women is considered in this paper. Based on joint toxicity of FQ observed in immature animals this class of antimicrobial agents is officially …