Comparison of the qSOFA and NEWS scores and the SIRS criteria in predicting outcomes in emergency department patients with and without infection: results from a prospective observational study

Objective. To compare the Quick Sequential (Sepsis-Related Organ Failure Assessment (qSOFA), National Early Warning Score (NEWS) and Systemic Inflammatory Response Syndrome (SIRS) scores value in predicting poor outcomes in emergency department patients with/without infection in Russia. Materials and Methods. This prospective observational study included data from 270 patients, of whom 132 (48.8%) patients had an infection and 138 (51.2%) did not have an infection. Comparison of areas under the ROC-curves (Receiver Operating Characteristic Curve) for the qSOFA, NEWS and SIRS scores in predicting the composite outcome (death and/or length of intensive care unit stay >1 day) was performed.

Role of Presepsin in Predicting ShortTerm Patient’s Status Changes and Preventing Excessive Antimicrobial Therapy in Patients with Nosocomial Infections

Relationship between presepsin values and shortterm status of patients with infections, as well as a correlation of presepsin levels and other markers of systemic inflammatory response were analyzed in this prospective observational study. The study …

Clinical and Laboratory Characteristics of Legionella Pneumonia Depending on Severity of the Disease

Objective. To determine characteristics of community-acquired Legionella pneumonia depending on severity of the disease, identify adverse reactions of long-term antimicrobial regimens, and calculate equation of prognosis of Legionella pneumonia severity upon hospital admission. Materials and Methods. A total of 61 patients with Legionella pneumonia were included and divided into 3 groups depending on the disease severity: Group 1 – 15 patients with non-severe pneumonia without systemic inflammatory response syndrome (SIRS), Group 2 – 32 patients with severe pneumonia and SIRS, Group 3 – 14 patients with very severe pneumonia.