polymyxins

Molecular epidemiology of mcr gene group

Clinical Microbiology and Antimicrobial Chemotherapy. 2020; 22(4):287-300
10.36488/cmac.2020.4.287-300
Colistin and polymyxin B are the “last reserve” antimicrobials for the treatment of extensively drug-resistant Gram-negative bacterial infections. The rapidly increasing prevalence of polymyxin resistance mediated by the mcr gene localized on plasmid …

Review of the international consensus guidelines for the optimal use of the polymyxins

Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(4):282-309
10.36488/cmac.2019.4.282-309
Polymyxins are often the only agents that remain in vitro active against extensively resistant bacterial pathogens. However, the use of polymyxins is compromised by the number of unresolved issues, including the technical aspects of antimicrobial …

Bacteriophage Preparations and Antibiotic Combinations: In vitro Activity Against Extensively Drug-Resistant Isolates of Pseudomonas aeruginosa ST235

Clinical Microbiology and Antimicrobial Chemotherapy. 2016; 18(4):242-248
The activity of 11 antibiotics combinations and 4 commercially available preparations for phagotherapy in regard to metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa clinical isolates of sequence type 235 (ST 235) belonging to the clonal …