Antibiotic dosing in obesity: size does matter?

Currently, from 15 to 50% of the population in the developed countries has obesity. Overall, patients with obesity have a higher risk of infection; they are more likely to develop infectious complications after surgical interventions and have a …

Gut Microbiota Composition in Patients with Different Body Weight

Objective. To characterize gut microbiota composition in patients with different body weight. Materials and Methods. A total of 92 patients (mean age: 52.8 years) with different body mass index (BMI), with or without abdominal obesity were enrolled in the study. A metagenomic analysis as an assessment of 16S rRNA gene diversity in a total DNA sample was performed according to 16S Metagenomic Sequencing Library Preparation protocol. Taxonomic composition of the samples was evaluated using 16S rRNA gene sequences database Greengenes v.