non-tuberculous mycobacteria | CMAC

non-tuberculous mycobacteria

Antimicrobial resistance of Mycobacterium avium during the COVID-19 pandemic

Objective. Conduct a comparative assessment of the frequency and spectrum of antimicrobial resistance of Mycobacterium avium isolated from patients of a phthisiopulmonology clinic in the pre-Covid period (2018–2019) and during the COVID-19 pandemic (2020–2023). Materials and Methods. The antimicrobial sensitivity of M. avium isolates was determined to 8 antimicrobial drugs: amikacin, clarithromycin, linezolid, moxifloxacin, ciprofloxacin, doxycycline, rifabutin, rifampicin. Drug susceptibility testing was performed using serial broth microdilution method according to published CLSI guidelines, M24S, 2023.

Species diversity of non-tuberculous mycobacteria isolated from patients in the “pre-Covid” period and during the COVID-19 pandemic

Objective. To compare the species diversity of non-tuberculous mycobacteria (NTM) isolated from patients of phthisiopulmonary institutions in 2018–2019 (“pre-Covid” period) and in 2020–2023 (during the COVID-19 pandemic). Materials and Methods. We identified 937 clinical isolates of NTM, isolated from patients undergoing differential diagnosis of tuberculosis and other respiratory diseases at The National Medical Research Center o Phthisiopulmonology and Infectious Diseases under the Ministry of Health of the Russian Federation (NMRC PhPI) and in other phthisiopulmonological institutions of the Russian Federation in 2018–2019 (“pre-Covid” period, n = 217) and in 2020–2023 (during the COVID-19 pandemic, n = 720).

Review of the international clinical practice guidelines for the treatment of lung infections caused by nontuberculous mycobacteria

Non-tuberculous mycobacteria (NTM) include more than 190 species and subspecies. Some NTM species can cause human diseases of the lungs or extrapulmonary infections. The guidelines focus on pulmonary mycobacteriosis in adult patients without cystic …

A current state of mycobacterioses

Mycobacterioses are caused by multiple opportunistic bacteria that are ubiquitous. The incidence rate of nontuberculosis mycobacterial infections (NTM) is rising due to an increased number of immunocompromised patients and advances in diagnosis. …