mycobacteriosis | CMAC

mycobacteriosis

Treatment of disseminated mycobacteriosis caused by Mycobacterium avium in HIV patients using bedaquiline: clinical examples

Three clinical cases of treatment of patients with disseminated mycobacteriosis caused by M. avium using the drug bedaquilin have been described. The criteria for prescribing bedaquiline were M. avium resistance to two drugs in the regimen (primarily …

Diagnosis and determination of resistance of non-tuberculous mycobacteria as a basis for clinical decision-making

Mycobacteriosis is an infectious disease caused by non-tuberculous mycobacteria (NTM), characterized by complicated verification, as it coincides in clinical, radiological and pathoanatomic characteristics with tuberculosis, the complexity of …

Species diversity of non-tuberculous mycobacteria isolated from patients in the “pre-Covid” period and during the COVID-19 pandemic

Objective. To compare the species diversity of non-tuberculous mycobacteria (NTM) isolated from patients of phthisiopulmonary institutions in 2018–2019 (“pre-Covid” period) and in 2020–2023 (during the COVID-19 pandemic). Materials and Methods. We identified 937 clinical isolates of NTM, isolated from patients undergoing differential diagnosis of tuberculosis and other respiratory diseases at The National Medical Research Center o Phthisiopulmonology and Infectious Diseases under the Ministry of Health of the Russian Federation (NMRC PhPI) and in other phthisiopulmonological institutions of the Russian Federation in 2018–2019 (“pre-Covid” period, n = 217) and in 2020–2023 (during the COVID-19 pandemic, n = 720).

A current state of mycobacterioses

Mycobacterioses are caused by multiple opportunistic bacteria that are ubiquitous. The incidence rate of nontuberculosis mycobacterial infections (NTM) is rising due to an increased number of immunocompromised patients and advances in diagnosis. …