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mutations

The rates of mutations associated with macrolide resistance in Mycoplasma genitalium among patients with non-gonococcal sexually transmitted infections in Smolensk and Tula

Clinical Microbiology and Antimicrobial Chemotherapy. 2019; 21(4):330-339
10.36488/cmac.2019.4.330-339
Objective. In this study, we examined the prevalence of macrolide-resistant M. genitalium in two Russian cities, Smolensk and Tula, between 2013 and 2017. Materials and Methods. DNA’s samples were isolated from urethral and cervicovaginal swabs using primary screening and tested for macrolide resistance-associated mutations by real-time PCR. This technology makes it possible to identify any nucleotide substitutions in the 23S rRNA M. genitalium gene at positions 2058, 2059, 2611 M.

Four cases of resistance mutations in 23S rRNA gene in Mycoplasma pneumoniae isolated from the hospitalized military personnel

Clinical Microbiology and Antimicrobial Chemotherapy. 2017; 19(3):248-253
Mycoplasma pneumoniae is a bacterial pathogen cause of upper and lower respiratory tract infections, transmitted by airborne droplets, causing outbreaks of pneumonia mainly in closed groups. According with recommendations, M. pneumoniae infections …

Molecular and Genetic Analysis of Influenza A Viruses with Different Sensitivity to Rimantadine, Based on the M2 Protein Gene Sequence

Clinical Microbiology and Antimicrobial Chemotherapy. 2007; 9(4):369-374
The paper presents the results of molecular analysis of epidemic strains of influenza A in different years and within subtypes H1 and H3, manifesting different sensitivity to rimantadine. Analysis was performed on the influenza A virus M2 protein …