modeling

Objective. To develop a quantitative model to assess the economic loss of irrational antimicrobial use and inaccurate antimicrobial resistance diagnosis. Materials and Methods. The model’s parameters were derived from a questionnaire survey designed to elucidate the characteristics of antimicrobial therapy practices and the impact of microbiological findings, including the frequency and consequences of diagnostic errors. The model’s fundamental structure rests upon the relationship between the accuracy of microbiological diagnoses, the likelihood of irrational antimicrobial therapy, and the consequent economic losses.

Pharmacoeconomic studies have become an integral part of evidence based medicine at nowadays. However, difficulties in standardization of pharmaeconomical analysis methods and problems with lifelong therapy of chronic pathologic processes …