methicillin resistance

Objective. To assess impact of the COVID-19 pandemic on the structure of pathogens causing periprosthetic joint infection (PJI) and the dynamics of their antibiotic resistance. Materials and Methods. A retrospective analysis of 379 strains of microorganisms isolated from patients with PJI of the knee and hip joints who underwent surgical treatment at the Federal Center for Traumatology and Orthopedics from 2018 to 2024 was performed. The biological material for the study was synovial fluid samples, tissue biopsies, aspirates from removed implants after ultrasonic treatment.

Objective. To evaluate Staphylococcus species diversity and methicillin resistance in nosocomial infections. Materials and Methods. Staphylococci isolated from blood, bronchoalveolar lavage fluid, cerebrospinal fluid, post-operative wound exudates, urine and other samples were identified to species level with MALDITOF mass-spectrometry. Methicillin resistance was evaluated according to EUCAST guidelines. Results. A total of 3239 consecutive Staphylococcus strains isolated in a tertiary-care medical centre, accumulating patients from all Russian regions were identified in 2016–2017 as 1460 (45.