Clinical Microbiology and Antimicrobial Chemotherapy. 2017; 19(4):321-326
Objective. Objectives. To research the qualitative relationships between the level of antimicrobial resistance and the level of consumption of different antimicrobial agents, and to further apply this knowledge to minimize the level of resistance.
Materials and Methods. An extensive simulation was performed based on the previously implemented model describing the relationship between a resistance and levels of antibiotic consumption. It makes possible to estimate the resistance growth rates in different antibiotic consumption strategies.