infections

Objective. To assess prevalence, etiology, antimicrobial prescribing practices and treatment outcomes of infections in intensive care units in Russia. Materials and Methods. A two-stage (the first stage – October 18, 2022, the second stage – November 18, 2022) multicenter prospective one-day observational study involved 111 intensive care units (ICUs) of 67 centers from 25 cities of the Russian Federation. Each patient was included in the study only once. Data from the medical records of all patients in the ICU on the day of the study were entered by the attending physician into a single electronic individual case report form.

Objective. To evaluate safety of anti-interleukin drugs used as a pathogenetic therapy of COVID-19 as assessed by risks of infectious complications. Materials and Methods. A systematic review of publications related to safety assessment of anti-interleukin drugs recommended as pathogenetic therapy in COVID-19 patients in terms of incidence of serious adverse events and adverse events of “Infections and Invasions” class and a meta-analysis of the data were performed. Results. The meta-analysis included 16 randomized and 3 non-randomized studies.

In connection with growing problem of antimicrobial resistance, the search for alternative treatments for infection is popular topic nowadays. This article represents an overview of published data on the therapeutic use of bacteriophages, …

Diabetic foot infections (DFIs) are a frequent clinical problem. Properly managed, most of them can be cured, but many patients needlessly undergo amputations because of improper diagnostic and therapeutic approaches. Foot infection should be defined …

Diabetic foot infections (DFI) are the major cause of non-traumatic amputations of lower extremities. Important predisposing factors for the development of DFI are peripheral neuropathy and diabetic angiopathy. The most common pathogen isolated in …

Translated and reprinted with permission from «Emerging Infectious Diseases» 1999;5:9-17.

We modeled estimates of the incidence, deaths, and direct medical costs of Staphylococcus aureus infections in hospitalized patients in the New York City …

Extension of spectrum of human bacterial pathogens as well as variety of their characteristics and unequal medical significance demand further study in order to extend the information on bacterial infections. This knowledge is necessary for …

Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes. These toxins, which affect eukaryotic …