infection

Translocation of gut microbiota in liver cirrhosis: mechanisms, clinical significance, and markers

This article is an overview of the data on bacterial intestinal translocation. The article reviews changes in the intestinal microbiome, the local physiological barrier, as well as the innate and adaptive immunity characteristics contributing to the …

Comparison of the qSOFA and NEWS scores and the SIRS criteria in predicting outcomes in emergency department patients with and without infection: results from a prospective observational study

Objective. To compare the Quick Sequential (Sepsis-Related Organ Failure Assessment (qSOFA), National Early Warning Score (NEWS) and Systemic Inflammatory Response Syndrome (SIRS) scores value in predicting poor outcomes in emergency department patients with/without infection in Russia. Materials and Methods. This prospective observational study included data from 270 patients, of whom 132 (48.8%) patients had an infection and 138 (51.2%) did not have an infection. Comparison of areas under the ROC-curves (Receiver Operating Characteristic Curve) for the qSOFA, NEWS and SIRS scores in predicting the composite outcome (death and/or length of intensive care unit stay >1 day) was performed.

Surveillance of antimicrobials use in neonatal hospitals with alternative DDD methods

One of the most common problems in neonatal hospitals is the choice of metrics of drugs usage in neonatology, especially use of antibiotics. This study represents our experience in quantifying antibiotic use in a Level-III neonatal intensive care …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Microbiological Aspects of Chronic Prostatitis

Chronic prostatitis/chronic pelvic pain syndrome is one of the most common diseases in urology which is difficult to diagnose and treat. According to current international guidelines, choice of approach to the management of patients with chronic …

Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock

Reproduced with permission from the Society of Critical Care Medicine, the European Society of Intensive Care and Medicine and the International Sepsis Forum.

Efficacy of Cefepime Monotherapy and The Combination of Ceftazidime with an Aminoglycoside in The Treatment of Infections in Oncology Patients with Severe Neutropenia

The combination of ceftazidime with an aminoglycoside is a commonly used standard for empiric therapy of febrile neutropenia. A lot of attention is paid to the development of effective monotherapy for the treatment of this condition. One of the most …