in vitro dynamic model | CMAC

in vitro dynamic model

Comparative Pharmacodynamics of Daptomycin and Vancomycin with Staphylococcus aureus in an in vitro Dynamic Model

Clinical Microbiology and Antimicrobial Chemotherapy. 2006; 8(2):186-192
To compare the pharmacodynamics of daptomycin (DAP) and vancomycin (VAN) as well as killing kinetics of S. aureus with different MICs were studied at widely ranged AUC/MIC ratios. Two clinical isolates, S. aureus 866 (MICDAP 0.35 µ/ml and MICVAN 0.70 …

Prevention of the Selection of Resistant Staphylococci in an in vitro Dynamic Model that Simulates Fluoroquinolone Pharmacokinetics

Clinical Microbiology and Antimicrobial Chemotherapy.2004; 6(3):252-259
To study the hypothesis of the mutant selection window (MSW) in a pharmacodynamic context, the susceptibility of a clinical isolate of methicillin-resistant Stap. hylococcus aureus exposed to moxifloxacin (MOX), levofloxacin (LEV) and ciprofloxacin …