Genomics | CMAC

Genomics

Genome-based analysis of the taxonomic structure of the genus Stenotrophomonas

Objective. To analyze the current taxonomic structure of the genus Stenotrophomonas based on genomic data, taking into account limitations associated with nomenclatural validation processes. Materials and Methods. A reference dataset was constructed using taxonomic information from LPSN (List of Prokaryotic names with Standing in Nomenclature) and genome assemblies retrieved from the NCBI database. Pairwise average nucleotide identity (ANI) and average amino acid identity (AAI) values were calculated. Species delineation was performed using the commonly accepted threshold of ANI ≥ 95%.

Cultivation and molecular characterization of complete genome sequences of M. pneumoniae isolated in Russia

Objective. In 2023–2014, a significant increase in the incidence of pneumonia caused by M. pneumoniae has been reported in Russia and China. Despite being one of the primary causative agents of community-acquired lower respiratory tract infections in children, due to the difficulties in obtaining a culture of this pathogen, the amount of genomic data on M. pneumoniae is currently extremely limited, with fewer than 300 genomic sequences available, of which only 79 are complete.