disease course

Objective. To study molecular and genetic features of M. tuberculosis (MTB) and human immunodeficiency virus (HIV) in patients with unfavorable course of HIV infection and tuberculosis. Materials and Methods. A total of 105 patients with HIV infection and newly diagnosed tuberculosis in whom tuberculosis was confirmed by microbiological and molecular genetic methods were included. The follow-up period was at least 6 months. Based on the results of the examination during treatment, all patients were divided into two groups: group 1 – patients with favorable course of HIV infection and tuberculosis (n = 78), group 2 – patients with unfavorable course of HIV infection and tuberculosis (n = 27).