community-acquired urinary tract infections

Antimicrobial resistance of pathogens causing community-acquired urinary tract infections in Russia: results of the multicenter study “DARMIS-2018”

Objective. To study in vitro activity of antimicrobials against clinical isolates from patients with communityacquired urinary tract infections (UTIs) in different regions of Russia in 2017–2018. Materials and Methods. A total of 1052 Enterobacterales isolates collected in the Russian Federation as part of a multicenter, prospective, epidemiological study of the antimicrobial resistance of uropathogens causing community-acquired UTI in different subsets of patients (“DARMIS-2018”) were included in the analysis. Uropathogens were isolated from children and adults of both sexes in all age groups with acute (and recurrences of chronic) community-acquired UTIs, including pregnant women with asymptomatic bacteriuria in 32 centers of 24 cities of Russia in 2017–2018.

Ceftibuten in the Treatment of Community-Acquired Urinary Tract Infections in Russia

Objective. Objectives. To investigate etiology and in vitro susceptibility of the most common pathogens causing community-acquired urinary tract infections (UTIs) in Russia. Materials and Methods. A total of 182 uropathogens isolated from urine samples of patients with communityacquired UTI were collected in Russia during 2013–2014 and included in the study. Results. Among the identified microorganisms the most prevalent uropathogens were Enterobacteriaceae (87,9%) and E. coli (68,1%). Drugs active against more than 90% of all Enterobacteriaceae isolates were fosfomycin (98,1%) and ceftibuten (93,1%).