cefiderocol

Objective. To assess the effects of chromosomal mutations on emergence of cefiderocol resistance among Pseudomonas aeruginosa clinical isolates. Materials and Methods. Study design purported to compare the characteristics of phenotypic antibiotic resistance and chromosomal mutations of P. aeruginosa strains of a common origin possessing different resistance levels to cefiderocol. Two P. aeruginosa isolates from the sputum of a patient with cystic fibrosis who had not previously received cefiderocol were analyzed.

Infectious complications in the respiratory tract caused by microorganisms from the Burkholderia cepacia complex are the main cause of death among patients with cystic fibrosis. Natural and acquired resistance mechanisms allow Burkholderia cepacia …