Candida albicans

Objective. To determine molecular biological characteristics of Candida albicans strains from patients with recurrent vulvovaginal candidiasis (RVVC) associated with the formation of resistance to azole drugs. Materials and Methods. The study included 36 clinical isolates of C. albicans from patients with RVVC who sought outpatient care at the P.N. Kashkin Research Institute of Medical Mycology from July to November 2024. Species identification of Candida spp. was performed using MALDI-TOF mass-spectrometry and targeted sequencing.

Objective. To evaluate the ability of bovhyaluronidaze azoximer to destroy biofilms formed by clinical strains of microorganisms. Materials and Methods. The study included 50 clinical strains of Staphylococcus aureus (n = 25), Staphylococcus epidermidis (n = 6), Enterococcus faecalis (n = 8), Escherichia coli (n = 9), Candida albicans (n = 2). Antimicrobial susceptibility testing was performed using broth microdilution method. Biofilm formation culturing in presence of antibiotics, or bovhyaluronidaze azoximer, or their combinations was assessed in Mueller-Hinton broth and brain heart broth in 96-well plates.

We present a case of fungal peritonitis in a patient secondary to intestinal perforation and repeated laparotomy. An analysis of data from the register of patients with invasive candidiasis is also presented. In the study were included 42 patients …